yes, but make sure impedance is correct (ohm)...
if the sub is dvc 4 ohm, u will need a 2ohm stable amp. most monoblocks can go to 2 ohm, but not 2ch or 4ch amps.
if the sub is dvc 2 ohm, u can wire it to 4ohm or 1 ohm. if the sub rms is 500w, u can either get a mono sub that gives 500W at 1ohm, or a 2ch amp that gives 500W at 4ohm bridged mono. a mono amp at 4ohm usually gives small power only, so only ppl who want to go lower than 4ohm will get monoblocks.